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In addition to intestinal L cells, GLP-1 is produced in the caudal nucleus of the solitary tract and in the ventro lateral medulla, 8 and GLP-1 receptors (GLP1R) are expressed in the hindbrain and in hypothalamic nuclei that are known to regulate energy balance
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GLP-1 receptor agonist promotes brown remodelling in mouse white adipose tissue through SIRT1
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