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These events stimulate the secretion of insulin, helping to compensate for insulin resistance triggered by new-onset diabetes.¹⁶ The drug also suppresses glucagon release by the pancreas, resulting in glucose-dependent reduction in plasma glucose and postprandial glucose by inhibiting hepatic glucose production and delaying gastric emptying.¹⁷ GLP-1s also act in brain regions associated with appetite and reward, reducing food intake and promoting weight loss

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Liraglutide (n=10)