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The older GLP-1 medications activate one or two receptors in the brain and throughout the body, whereas retatrutide works by activating three receptors
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Check with your Care Team before using anti-diarrhea medications like Imodium, as they may not always be the best solution
![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
