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Animal studies have demonstrated that GLP-1 receptor activation can reduce preference for palatable, high-sugar foods and decrease reward-driven eating behaviours

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Keywords: glucagon-like peptide-1, metabolic disease, type 2 diabetes, enteroendocrine cell system, GPCR, L-cells, microbiome, α-cells Introduction The gastrointestinal (GI) tract is a complex organ that monitors the body's energetical state and provides it with water and macro and micronutrients extracted from the ingested food